TG is a protein made by cells in the thyroid. The thyroid is a small, butterfly-shaped gland located near the throat. A thyroglobulin test is mostly used as a tumor marker test to help guide thyroid cancer treatment.

TSH is a pituitary hormone that stimulates the thyroid gland to produce thyroxine (T4), and then triiodothyronine (T3) which stimulates the metabolism of almost every tissue in the body.It is a glycoprotein hormone produced by thyrotrope cells in the anterior pituitary gland, which regulates the endocrine function of the thyroid.